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4-Octyl itaconate

CAS No. 3133-16-2

4-Octyl itaconate ( 4-Octyl Itaconate; 4 Octyl Itaconate; 4-Octyl-Itaconate )

产品货号. M18412 CAS No. 3133-16-2

4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥340 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    4-Octyl itaconate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
  • 产品描述
    4-Octyl Itaconate is a cell permeable activator of Nrf2 which inhibits LPS-induced increases in IL-1β mRNA, HIF-1α, and IL-10 in macrophages.
  • 同义词
    4-Octyl Itaconate; 4 Octyl Itaconate; 4-Octyl-Itaconate
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Keap1-Nrf2
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    3133-16-2
  • 分子量
    242.31
  • 分子式
    C13H22O4
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 150 mg/mL; 619.04 mM
  • SMILES
    CCCCCCCCOC(=O)CC(=C)C(O)=O
  • 化学全称
    2-Methylene-4-(octyloxy)-4-oxobutanoic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.
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