4-Octyl itaconate
CAS No. 3133-16-2
4-Octyl itaconate ( 4-Octyl Itaconate; 4 Octyl Itaconate; 4-Octyl-Itaconate )
产品货号. M18412 CAS No. 3133-16-2
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
50MG | ¥340 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称4-Octyl itaconate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
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产品描述4-Octyl Itaconate is a cell permeable activator of Nrf2 which inhibits LPS-induced increases in IL-1β mRNA, HIF-1α, and IL-10 in macrophages.
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同义词4-Octyl Itaconate; 4 Octyl Itaconate; 4-Octyl-Itaconate
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通路Others
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靶点Other Targets
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受体Keap1-Nrf2
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研究领域——
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适应症——
化学信息
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CAS Number3133-16-2
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分子量242.31
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分子式C13H22O4
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纯度98%
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溶解度DMSO : ≥ 150 mg/mL; 619.04 mM
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SMILESCCCCCCCCOC(=O)CC(=C)C(O)=O
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化学全称2-Methylene-4-(octyloxy)-4-oxobutanoic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.
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