4-Octyl itaconate ( 4-Octyl Itaconate | 4 Octyl Itaconate | 4-Octyl-Itaconate )

产品货号. M18412 CAS No. 3133-16-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

4-Octyl itaconate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

4-Octyl Itaconate 是一种细胞渗透性衣康酸酯衍生物。衣康酸是一种抗炎代谢物，可通过 KEAP1 的烷基化激活 Nrf2。
产品描述

4-Octyl Itaconate is a cell permeable activator of Nrf2 which inhibits LPS-induced increases in IL-1β mRNA, HIF-1α, and IL-10 in macrophages.
体外实验

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体内实验

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同义词

4-Octyl Itaconate | 4 Octyl Itaconate | 4-Octyl-Itaconate
通路

Others
靶点

Other Targets
受体

Keap1-Nrf2
研究领域

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适应症

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1.Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.

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